Richards Duncan
GlaxoSmithKline Academic Discovery Performance Unit, GSK R&D Addenbrookes Hospital, Hills Road, Cambridge CB2 2GG, UK.
Br J Clin Pharmacol. 2012 Jun;73(6):870-3. doi: 10.1111/j.1365-2125.2012.04227.x.
The challenges of developing new medicines are well known. Effective application of clinical pharmacology expertise is vital to the successful evaluation of potential new medicines. In drug development, this depends on effective integration of diverse skills. Many of these are currently in short supply, but through innovative partnerships between industry and academia there is an opportunity to reinvigorate the discipline by nurturing these key skills to the benefit of both partners. Specific areas of focus should be experimental medicine, modelling and simulation, and translational skills.
开发新药面临的挑战是众所周知的。临床药理学专业知识的有效应用对于成功评估潜在新药至关重要。在药物研发中,这依赖于多种技能的有效整合。目前其中许多技能短缺,但通过行业与学术界之间的创新合作关系,有机会通过培养这些关键技能来重振该学科,使双方都受益。具体的重点领域应该是实验医学、建模与模拟以及转化技能。