Xu Xuan, Li Dandan, Zhao Shuyu, Liu Xicheng, Feng Zhichun, Ding Hui
Centre of Children's Advanced Disease, Bayi Children's Hospital Affiliated to General Hospital of Beijing Military Commond, Beijing, China.
Interact Cardiovasc Thorac Surg. 2012 May;14(5):548-50. doi: 10.1093/icvts/ivs018. Epub 2012 Feb 22.
The aim of this study was to evaluate the use of balloon-expandable metallic stents in the treatment of children with congenital tracheal stenosis in whom conventional therapy has failed. From 2010 to 2011, balloon-expandable metallic stents were implanted into the trachea of eight infants aged 2-20 months in the paediatric intensive care unit. The infants had severe airway obstruction caused by congenital tracheal stenosis. Tracheal stents were placed after intraluminal balloon dilatation of the tracheal stenosis, inserted with balloon catheters and implanted into the desired position bronchoscopically. The stents were 12 to 29 mm long and 4 mm in diameter. Seven children were relieved of airway obstruction after this procedure. However, a child died due to severe sepsis after the placement of bronchial stents. No granulation tissue developed over the stents in any of the children. Stents have been in place for 1-6 months after insertion without any other complication. Balloon-expandable metallic stents are effective in relieving airway obstruction by congenital tracheal stenosis in children. This technique may provide an important remedy for congenital tracheal stenosis in children.
本研究的目的是评估球囊扩张金属支架在治疗常规治疗失败的先天性气管狭窄儿童中的应用。2010年至2011年期间,在儿科重症监护病房,将球囊扩张金属支架植入8名年龄在2至20个月的婴儿气管内。这些婴儿患有由先天性气管狭窄引起的严重气道阻塞。在气管狭窄进行腔内球囊扩张后放置气管支架,通过球囊导管插入并在支气管镜下植入到所需位置。支架长度为12至29毫米,直径为4毫米。7名儿童在此手术后气道阻塞得到缓解。然而,一名儿童在放置支气管支架后因严重脓毒症死亡。所有儿童的支架上均未形成肉芽组织。支架植入后已在位1至6个月,无任何其他并发症。球囊扩张金属支架在缓解儿童先天性气管狭窄引起的气道阻塞方面是有效的。该技术可能为儿童先天性气管狭窄提供一种重要的治疗方法。