Viken R J, Johnson A K, Murray B
Department of Psychology, Indiana University, Bloomington 47405.
Physiol Behav. 1990 Jul;48(1):203-5. doi: 10.1016/0031-9384(90)90286-d.
F1 Offspring of hypertensive and normotensive rats (BHR) were reared with either hypertensive (SHR) or normotensive (WKY) cagemates, and observations were conducted at two developmental periods to assess the effects of rearing condition on the social environment and the behavior of BHR subjects. SHR displayed significantly more agonistic behavior during development than WKY, and BHR subjects reared with SHR were the targets of significantly more agonistic behavior than BHR subjects reared with WKY cagemates. BHR reared with SHR initiated twice as much agonistic behavior as BHR reared with WKY. When heart rate and blood pressure were assessed at 75-80 days of age, however, neither the alterations in developmental social environment nor the alterations in the behavioral characteristics of BHR were associated with differences in cardiovascular variables. The results do not support a causal connection between behavioral characteristics and cardiovascular outcome.
高血压大鼠和血压正常大鼠（BHR）的F1代子代与高血压（SHR）或血压正常（WKY）的同笼伙伴一起饲养，并在两个发育阶段进行观察，以评估饲养条件对BHR受试动物社交环境和行为的影响。SHR在发育过程中表现出的攻击性行为明显多于WKY，与SHR一起饲养的BHR受试动物比与WKY同笼伙伴一起饲养的BHR受试动物成为更多攻击性行为的目标。与WKY一起饲养的BHR发起的攻击性行为是与SHR一起饲养的BHR的两倍。然而，在75 - 80日龄评估心率和血压时，BHR发育社交环境的改变或行为特征的改变均与心血管变量的差异无关。结果不支持行为特征与心血管结局之间存在因果关系。
