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再生障碍性贫血患者血小板输注后迟发支架内血栓形成 1 例

A case of late stent thrombosis following platelet transfusion in a patient with aplastic anemia.

机构信息

Division of Cardiovascular Medicine, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.

出版信息

Korean Circ J. 2012 Jan;42(1):54-7. doi: 10.4070/kcj.2012.42.1.54. Epub 2012 Jan 31.

DOI:10.4070/kcj.2012.42.1.54
PMID:22363385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3283756/
Abstract

Aplastic anemia is a condition in which the bone marrow fails to produce adequate numbers of peripheral blood elements. The incidences of atherosclerosis and myocardial infarction in patients with congenital coagulation disorders and chronic thrombocytopenia are very low. In this paper, a case of late stent thrombosis within a drug-eluting stent occurring after platelet transfusion in a patient with aplastic anemia is presented. The authors' observations emphasize the risks of platelet transfusion and the authors' support withholding such a treatment unless vitally indicated, in patients with coronary artery stent implantation and even in those on dual antiplatelet therapy.

摘要

再生障碍性贫血是一种骨髓无法产生足够数量外周血成分的疾病。先天性凝血障碍和慢性血小板减少症患者发生动脉粥样硬化和心肌梗死的几率非常低。本文报道了一例再生障碍性贫血患者在输注血小板后发生药物洗脱支架内晚期支架血栓形成的病例。作者的观察结果强调了血小板输注的风险，作者支持除非有生命危险，否则应避免对冠状动脉支架植入术后的患者，甚至对正在接受双联抗血小板治疗的患者进行这种治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82b/3283756/46f505ebb6cf/kcj-42-54-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82b/3283756/f61069f016ec/kcj-42-54-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82b/3283756/4a17c9fc816f/kcj-42-54-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82b/3283756/46f505ebb6cf/kcj-42-54-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82b/3283756/f61069f016ec/kcj-42-54-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82b/3283756/4a17c9fc816f/kcj-42-54-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82b/3283756/46f505ebb6cf/kcj-42-54-g003.jpg

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本文引用的文献

1
Acute stent thrombosis in a patient with giant cell arteritis.巨细胞动脉炎患者发生急性支架内血栓形成。
Can J Cardiol. 2008 Apr;24(4):e25-6. doi: 10.1016/s0828-282x(08)70186-7.
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Coronary stent occlusion after platelet transfusion: a case series.
J Invasive Cardiol. 2007 Oct;19(10):E297-9.
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急性心肌梗死合并再生障碍性贫血的病因是什么？一例病例报告及文献综述。
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Towards increasing shelf life and haemostatic potency of stored platelet concentrates.为了提高储存血小板浓缩物的货架寿命和止血效力。
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Plasminogen activator inhibitor-1, which is released from blood product transfusions, might be associated with (sub)acute thrombosis after coronary dilatation and stenting: a case report.纤溶酶原激活物抑制剂-1由输血制品释放，可能与冠状动脉扩张和支架置入术后的（亚）急性血栓形成有关：一例报告。
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Thrombotic complications after intravenous immunoglobulin therapy in two patients.两名患者静脉注射免疫球蛋白治疗后的血栓形成并发症。
Pharmacotherapy. 2002 Dec;22(12):1638-41. doi: 10.1592/phco.22.17.1638.34125.
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