Division of Cardiovascular Medicine, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
Korean Circ J. 2012 Jan;42(1):54-7. doi: 10.4070/kcj.2012.42.1.54. Epub 2012 Jan 31.
Aplastic anemia is a condition in which the bone marrow fails to produce adequate numbers of peripheral blood elements. The incidences of atherosclerosis and myocardial infarction in patients with congenital coagulation disorders and chronic thrombocytopenia are very low. In this paper, a case of late stent thrombosis within a drug-eluting stent occurring after platelet transfusion in a patient with aplastic anemia is presented. The authors' observations emphasize the risks of platelet transfusion and the authors' support withholding such a treatment unless vitally indicated, in patients with coronary artery stent implantation and even in those on dual antiplatelet therapy.
再生障碍性贫血是一种骨髓无法产生足够数量外周血成分的疾病。先天性凝血障碍和慢性血小板减少症患者发生动脉粥样硬化和心肌梗死的几率非常低。本文报道了一例再生障碍性贫血患者在输注血小板后发生药物洗脱支架内晚期支架血栓形成的病例。作者的观察结果强调了血小板输注的风险,作者支持除非有生命危险,否则应避免对冠状动脉支架植入术后的患者,甚至对正在接受双联抗血小板治疗的患者进行这种治疗。