Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia, United States of America.
PLoS One. 2012;7(2):e30609. doi: 10.1371/journal.pone.0030609. Epub 2012 Feb 17.
A substantial proportion of men who have sex with men (MSM) in the United States remain unvaccinated against hepatitis B. We sought to understand which factors are associated with vaccination among HIV-negative MSM.
METHODOLOGY/PRINCIPAL FINDINGS: Data were from a 2010 web-based survey of adult MSM. We calculated the prevalence of self-reported hepatitis B vaccination among 1,052 HIV-negative or HIV-untested men who knew their hepatitis B vaccination status, and used multivariate logistic regression to determine associated factors. 679 (64.5%) MSM reported being vaccinated. Younger men were more likely to report being vaccinated than older men, and there was a significant interaction between age and history of hepatitis B testing. Men with at least some college education were at least 2.1 times as likely to be vaccinated as men with a high school education or less (95% CI = 1.4-3.1). Provider recommendation for vaccination (aOR = 4.2, 95% CI = 2.4-7.4) was also significantly associated with receipt of vaccination.
CONCLUSIONS/SIGNIFICANCE: Providers should assess sexual histories of male patients and offer those patients with male sex partners testing for hepatitis infection and vaccinate susceptible patients. There may be particular opportunities for screening and vaccination among older and more socioeconomically disadvantaged MSM.
在美国，相当一部分男男性行为者（MSM）未接种乙型肝炎疫苗。我们试图了解哪些因素与 HIV 阴性 MSM 的疫苗接种有关。
方法/主要发现：数据来自于 2010 年一项针对成年 MSM 的网络调查。我们计算了 1052 名已知乙型肝炎疫苗接种状况的 HIV 阴性或未经 HIV 检测的 MSM 中自我报告的乙型肝炎疫苗接种率，并使用多变量逻辑回归来确定相关因素。679 名（64.5%）MSM 报告接种了疫苗。年轻男性比老年男性更有可能报告接种疫苗，且年龄和乙型肝炎检测史之间存在显著交互作用。至少接受过一些大学教育的男性接种疫苗的可能性至少是接受过高中或以下教育的男性的 2.1 倍（95%CI=1.4-3.1）。接种疫苗的提供者建议（OR=4.2，95%CI=2.4-7.4）也与接种疫苗显著相关。
结论/意义：提供者应评估男性患者的性病史，并为有男性性伴侣的患者提供乙型肝炎感染检测和接种疫苗的服务。在年龄较大和社会经济地位较低的 MSM 中，可能存在特别的筛查和接种疫苗的机会。
