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Fibroblast growth factor 21: a novel metabolic regulator.

作者信息

Seo Ji A, Kim Nan Hee

机构信息

Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University Ansan Hospital, Asan, Korea.

出版信息

Diabetes Metab J. 2012 Feb;36(1):26-8. doi: 10.4093/dmj.2012.36.1.26. Epub 2012 Feb 17.

Abstract
摘要

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本文引用的文献

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Various oscillation patterns of serum fibroblast growth factor 21 concentrations in healthy volunteers.
Diabetes Metab J. 2012 Feb;36(1):29-36. doi: 10.4093/dmj.2012.36.1.29. Epub 2012 Feb 17.
2
Time-imposed daily restricted feeding induces rhythmic expression of Fgf21 in white adipose tissue of mice.
Biochem Biophys Res Commun. 2011 Aug 26;412(2):396-400. doi: 10.1016/j.bbrc.2011.07.125. Epub 2011 Aug 3.
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Plasma FGF21 displays a circadian rhythm during a 72-h fast in healthy female volunteers.
Clin Endocrinol (Oxf). 2011 Oct;75(4):514-9. doi: 10.1111/j.1365-2265.2011.04084.x.
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Circadian rhythm of circulating fibroblast growth factor 21 is related to diurnal changes in fatty acids in humans.
Clin Chem. 2011 May;57(5):691-700. doi: 10.1373/clinchem.2010.155184. Epub 2011 Feb 15.
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Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease.
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Obesity is a fibroblast growth factor 21 (FGF21)-resistant state.
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Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway.
Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12553-8. doi: 10.1073/pnas.1006962107. Epub 2010 Jun 28.
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Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease.
Gastroenterology. 2010 Aug;139(2):456-63. doi: 10.1053/j.gastro.2010.04.054. Epub 2010 May 5.
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Regulation of FGF21 expression and secretion by retinoic acid receptor-related orphan receptor alpha.
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