Division of Mental Health and Addiction, Building 49, Oslo University Hospital-Ullevål, PO Box 4956, Nydalen, 0424 Oslo, Norway.
Expert Rev Neurother. 2012 Mar;12(3):353-9. doi: 10.1586/ern.11.191.
Suicidal behavior and suicide is prevalent in schizophrenia, with an estimated lifetime risk of approximately 5%. The risk is particularly high in the early phases of the disorder, and especially during the years around treatment initiation. Suicide attempts before first treatment contact are also prevalent, with the risk of suicide attempt associated with the length of untreated illness. Several risk factors are in common with the general population, and include previous suicide attempts, impulsive personality traits, substance abuse, depression and feelings of hopelessness. Recent research examines how patients' subjective experiences, including their insight into having a severe mental illness and their beliefs about mental illnesses, may influence suicidal behavior. In this article, we will present a review of studies illustrating the complex background of suicide risk in schizophrenia, with a particular emphasis on the role of insight in the early phases of schizophrenia.
自杀行为和自杀在精神分裂症中很常见,估计终生风险约为 5%。在疾病的早期阶段,风险特别高,尤其是在开始治疗的几年期间。在首次治疗接触之前尝试自杀也很常见,自杀未遂的风险与未治疗疾病的时间长短有关。一些风险因素与一般人群相同,包括以前的自杀企图、冲动的个性特征、物质滥用、抑郁和绝望感。最近的研究探讨了患者的主观体验,包括他们对严重精神疾病的认识以及他们对精神疾病的信念,如何影响自杀行为。在本文中,我们将回顾一些研究,说明精神分裂症自杀风险的复杂背景,特别强调洞察力在精神分裂症早期阶段的作用。