Pollock V E, Schneider L S
Department of Psychiatry, University of Southern California School of Medicine, Los Angeles.
Psychophysiology. 1990 Jul;27(4):438-44. doi: 10.1111/j.1469-8986.1990.tb02340.x.
Some previous quantitative EEG research indicates that depressed subjects show increased alpha and beta compared to controls. In this report, absolute and relative amplitude measures of topographic EEG were used to compare elderly subjects with major depression to sex and age matched control subjects. Elderly depressed subjects showed significantly higher absolute alpha amplitude than controls, but regional differences did not specifically distinguish them. Relative alpha amplitudes, and absolute and relative measures of beta, delta, and theta did not reliably distinguish depressed and control subjects. The results are discussed in the context of previous EEG research in depression and the elderly. Methodological features and the implications of these findings for state and trait dependent conceptualizations of depression are considered.
先前的一些定量脑电图研究表明，与对照组相比，抑郁症患者的阿尔法波和贝塔波有所增加。在本报告中，使用脑电图地形图的绝对和相对振幅测量方法，将患有重度抑郁症的老年受试者与性别和年龄匹配的对照受试者进行比较。老年抑郁症患者的绝对阿尔法波振幅显著高于对照组，但区域差异并未明确区分他们。相对阿尔法波振幅以及贝塔波、德尔塔波和西塔波的绝对和相对测量值并不能可靠地区分抑郁症患者和对照受试者。将结合先前关于抑郁症和老年人的脑电图研究来讨论这些结果。考虑了方法学特征以及这些发现对抑郁症的状态和特质相关概念化的影响。
