Institute of Health and Biomedical Innovation/School of Public Health, Victoria Park Road, Kelvin Grove 4059, Australia.
Appetite. 2012 Aug;59(1):194-9. doi: 10.1016/j.appet.2012.02.016. Epub 2012 Feb 21.
The aim of this paper was to investigate the association between appetite and kidney-disease specific quality of life in maintenance hemodialysis patients. Quality of life (QoL) was measured using the kidney disease quality of life survey. Appetite was measured using self-reported categories and a visual analog scale. Other nutritional parameters included Patient-Generated Subjective Global Assessment (PGSGA), dietary intake, body mass index and biochemical markers C-reactive protein and albumin. Even in this well nourished sample (n=62) of hemodialysis patients, PGSGA score (r=-0.629), subjective hunger sensations (r=0.420) and body mass index (r=-0.409) were all significantly associated with the physical health domain of QoL. As self-reported appetite declined, QoL was significantly lower in nine domains which were mostly in the SF36 component and covered social functioning and physical domains. Appetite and other nutritional parameters were not as strongly associated with the Mental Health domain and Kidney Disease Component Summary Domains. Nutritional parameters, especially PGSGA score and appetite, appear to be important components of the physical health domain of QoL. As even small reductions in nutritional status were associated with significantly lower QoL scores, monitoring appetite and nutritional status is an important component of care for hemodialysis patients.
本文旨在探讨维持性血液透析患者的食欲与肾脏疾病特异性生活质量之间的关系。生活质量（QoL）采用肾脏病生活质量调查进行测量。食欲采用自我报告类别和视觉模拟量表进行测量。其他营养参数包括患者生成的主观整体评估（PGSGA）、饮食摄入、体重指数和生化标志物 C 反应蛋白和白蛋白。即使在这个营养状况良好的血液透析患者样本（n=62）中，PGSGA 评分（r=-0.629）、主观饥饿感（r=0.420）和体重指数（r=-0.409）与 QoL 的生理健康领域均显著相关。随着自我报告的食欲下降，在九个领域的 QoL 显著降低，这些领域主要在 SF36 成分中，涵盖社会功能和身体领域。食欲和其他营养参数与心理健康领域和肾脏病成分综合领域的相关性并不强。营养参数，尤其是 PGSGA 评分和食欲，似乎是 QoL 生理健康领域的重要组成部分。由于营养状况的微小下降与 QoL 评分的显著降低相关，因此监测食欲和营养状况是血液透析患者护理的重要组成部分。
