Marini M, Guerrisi R, Vidiri A, Ponzio R
Dipartimento di Medicina Sperimentale, Università La Sapienza, Roma.
Radiol Med. 1990 Sep;80(3):263-71.
Bone alterations in the patients undergoing periodic dialysis represent a frequent and invalidating complication and cause the pattern called uremic osteodystrophy. In this study we have examined 173 pelvic X-rays of 73 patients affected with chronic renal insufficiency and undergoing periodic dialysis. The results indicate the presence of all the lesions characterizing uremic osteodystrophy. Arterial calcifications and osteoporosis are the most frequent patterns; with various incidence, osteomalacia, osteitis fibrosa, osteosclerosis and brown tumors are associated. In this group of patients, who were followed for many years, a non-univocal behavior was observed: next to patterns of progressive aggravation, such as vascular calcifications, phases of stabilization/improvement were observed, e.g., in case of brown tumors and osteitis fibrosa.
接受定期透析的患者出现骨骼改变是一种常见且致残的并发症，会导致所谓的尿毒症骨营养不良。在本研究中，我们检查了73例慢性肾功能不全且接受定期透析患者的173张骨盆X光片。结果显示存在尿毒症骨营养不良的所有特征性病变。动脉钙化和骨质疏松是最常见的类型；骨软化、纤维性骨炎、骨硬化和棕色瘤也有不同程度的发生。在对这组患者进行多年随访后，观察到一种不单一的情况：除了血管钙化等进行性加重的类型外，还观察到了稳定/改善阶段，例如棕色瘤和纤维性骨炎的情况。
