Department of Psychiatry, Beer Yaakov Mental Health Center, PO Box 1, Beer Yaakov 70350, Israel.
J Med Ethics. 2012 Jul;38(7):442-4. doi: 10.1136/medethics-2011-100217. Epub 2012 Feb 25.
In patients with schizophrenia, consent postmortem for organ donation for transplantation and research is usually obtained from relatives. By means of a questionnaire, the authors investigate whether patients with schizophrenia would agree to family members making such decisions for them as well as compare decisions regarding postmortem organ transplantation and brain donation between patients and significant family members. Study results indicate while most patients would not agree to transplantation or brain donation for research, a proportion would agree. Among patients who declined organ donation for transplantation or brain research, almost half of family members would have agreed to brain donation for research and over 40% to organ transplantation. Male relatives are more likely to agree to organ donation from their deceased relatives for both transplantation and research. The authors argue that it is important to respect autonomy and interests of research subjects even if mentally ill and even if no longer living. Consent may be assisted by appropriate educational interventions prior to patient death.
在精神分裂症患者中，通常会从亲属那里获得死后器官捐献用于移植和研究的同意。作者通过问卷调查的方式，调查精神分裂症患者是否会同意亲属为他们做出这样的决定，并比较患者和重要亲属对死后器官移植和大脑捐赠的决定。研究结果表明，大多数患者不会同意死后器官用于移植或研究，但仍有一部分患者会同意。在拒绝死后器官用于移植或脑研究的患者中，近一半的家属会同意捐献大脑用于研究，超过 40%的家属会同意器官移植。男性亲属更有可能同意捐献其已故亲属的器官，用于移植和研究。作者认为，即使是精神疾病患者，即使已经去世，也应该尊重研究对象的自主权和利益。在患者去世前，可以通过适当的教育干预来协助获得同意。
