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经皮途径用于维持和挽救功能不良的自体透析血管通路

Percutaneous approach in the maintenance and salvage of dysfunctional autologous vascular access for dialysis.

作者信息

De Rango Paola, Parente Basso, Cieri Enrico, Bonanno Paolo, Farchioni Luca, Manzone Alessandra, Verzini Fabio

机构信息

Unit of Vascular and Endovascular Surgery, Hospital S. M. Misericordia and University of Perugia, Perugia, Italy.

出版信息

J Vasc Access. 2012 Jul-Sep;13(3):381-7. doi: 10.5301/jva.5000060.

Abstract

PURPOSE

Endovascular procedures have been increasingly used for salvage of failing vascular access with conflicting results. The aim of this study was to assess the mid-term patency and complication rates of angioplasty procedures performed in a single center for treatment of stenosis compromising vascular accesses.

METHODS

A prospective database of vascular accesses performed in 2006-2010 was investigated. The endovascular approach was applied following a standardized protocol by a dedicated team. A total of 531 consecutive procedures were reviewed (326 men; mean age 70.94 years). Patency rates were estimated using the Kaplan-Meier method.

RESULTS

There were 199 procedures for failing access: 135 were surgical and 64 angioplasties performed for anastomosis (n=27), venous (n=45) or arterial (n=7) stenosis. Immediate technical success of endovascular procedures was 95.3%(61/64); complication rate was 6.3% (4/64). Primary patency rates were 55% at six months, 49% at 12 months, and 21% at 24 months. In the concurrent group of 135 open procedures, primary patency rates were 80% at six months and 67% at 12 months (P=.002); nevertheless, at 24 months, patency was as low as 49%. Cost estimates for angioplasty revealed additional fees ranging from 411.34 to 446.34 Euro with respect to open surgical procedures.

CONCLUSIONS

Most dysfunctional vascular accesses can be successfully and safely treated by the endovascular route. In spite of poor mid-term durability, the angioplasty balloon might be considered as a bridge, effective, and repeatable solution with reasonable costs to prolong access survival avoiding additional surgery. The failure rate in the mid-term for dysfunctional vascular access may also be high after surgical reintervention.

摘要

目的

血管内介入手术越来越多地用于挽救功能衰竭的血管通路,但结果存在争议。本研究的目的是评估在单一中心进行的血管成形术治疗危及血管通路的狭窄的中期通畅率和并发症发生率。

方法

对2006年至2010年进行的血管通路前瞻性数据库进行调查。由专业团队按照标准化方案采用血管内入路。共回顾了531例连续手术(326例男性;平均年龄70.94岁)。使用Kaplan-Meier方法估计通畅率。

结果

有199例手术用于处理功能衰竭的通路:135例为外科手术,64例为血管成形术,用于吻合口(n = 27)、静脉(n = 45)或动脉(n = 7)狭窄。血管内手术的即刻技术成功率为95.3%(61/64);并发症发生率为6.3%(4/64)。6个月时的初级通畅率为55%,12个月时为49%,24个月时为21%。在135例开放手术的同期组中,6个月时的初级通畅率为80%,12个月时为67%(P = 0.002);然而,在24个月时,通畅率低至49%。血管成形术的成本估计显示,相对于开放手术,额外费用在411.34欧元至446.34欧元之间。

结论

大多数功能失调的血管通路可通过血管内途径成功、安全地治疗。尽管中期耐久性较差,但血管成形术球囊可被视为一种桥梁,是一种有效、可重复且成本合理的解决方案,可延长通路存活时间,避免额外手术。功能失调的血管通路中期失败率在手术再次干预后可能也很高。

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