计算机断层扫描在诊断孤立性肺结节恶性病变中的准确性。

Accuracy of computed tomography in diagnosing malignancy in solitary pulmonary lesions.

作者信息

Memon Wasim, Husen Yousuf, Akhtar Waseem, Sophie Raafay, Baig Muhammad Akbar

机构信息

Department of Diagnostic Radiology, Aga Khan University Hospital, Karachi.

出版信息

J Pak Med Assoc. 2011 Jan;61(1):48-51.

PMID:22368902

Abstract

OBJECTIVE

To evaluate accuracy of Computed Tomography (CT) for diagnosing malignancy in solitary pulmonary lesions (SPLs).

METHODS

A prospective cross-sectional study was conducted from 20-01-2007 to 30-06-2008 at the Radiology department, Aga Khan University Hospital (AKUH) Karachi. Fifty-three patients with solitary pulmonary lesions (SPLs) seen in prior chest x-rays or chest CT scans were referred to radiology department for CT guided biopsy. CT scan was performed for each patient prior to biopsy and CT evaluation of the SPLs was performed followed by CT guided Biopsy. Histopathological diagnosis of the lesion was taken as the gold standard.

RESULTS

CT was found to be 100% sensitive, 30% specific and 87% accurate for diagnosing malignancy in solitary pulmonary lesions while PPV and NPV were 86% and 100% respectively.

CONCLUSION

CT scan is highly sensitive yet non-specific and cannot be used as the definitive diagnostic modality for diagnosing malignancy in solitary pulmonary lesions.

摘要

目的

评估计算机断层扫描（CT）对孤立性肺结节（SPL）恶性病变的诊断准确性。

方法

2007年1月20日至2008年6月30日在卡拉奇阿迦汗大学医院（AKUH）放射科进行了一项前瞻性横断面研究。53例先前胸部X线或胸部CT扫描发现有孤立性肺结节（SPL）的患者被转诊至放射科进行CT引导下活检。活检前对每位患者进行CT扫描，并对SPL进行CT评估，随后进行CT引导下活检。以病变的组织病理学诊断作为金标准。