Liniger C, Feldmeyer J J, Baumann K
Unité de traitement et d'enseignement pour diabétiques, Hôpital cantonal universitaire, Genève.
Schweiz Rundsch Med Prax. 1990 Oct 9;79(41):1208-12.
Neuropathy is a frequent late complication of diabetes. The severity and duration of hyperglycaemia are probably the principal causal factor. The consequences of the effects of neuropathy on the lower-limb and the autonomic nervous system are major causes of morbidity. Apart from glycaemic control, no specific treatment is yet available, but measures for symptomatic alleviation of certain painful and visceral manifestations of diabetic neuropathy exist and are outlined in these guidelines. The guidelines also describe simple diagnostic strategies for detecting potentially threatening neurological signs, notably reduction or loss of lower-limb sensation which expose the patient to the risk of ulceration, unnoticed trauma and amputation. The guidelines also summarize the preventive educational measures required to minimize these risks.
神经病变是糖尿病常见的晚期并发症。高血糖的严重程度和持续时间可能是主要病因。神经病变对下肢和自主神经系统造成的影响是发病的主要原因。除血糖控制外，目前尚无特效治疗方法，但本指南概述了缓解糖尿病神经病变某些疼痛和内脏表现的对症措施。指南还介绍了用于检测潜在威胁性神经体征的简单诊断策略，尤其是下肢感觉减退或丧失，这会使患者面临溃疡、未察觉的创伤和截肢风险。指南还总结了将这些风险降至最低所需的预防性教育措施。
