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[虚拟支气管镜检查与纤维支气管镜检查——中央型肺肿瘤评估中诊断价值的比较]

[Virtual bronchoscopy and bronchofiberoscopy--a comparison of diagnostic value in assessment of centrally localized lung tumor].

作者信息

Radwan-Röhrenschef Piotr, Burakowska Barbara

机构信息

I Klinika Chorób Płuc IGiChP, ul. Płocka 26, Warsaw.

出版信息

Pneumonol Alergol Pol. 2012;80(2):127-39.

PMID:22370981
Abstract

INTRODUCTION

Virtual bronchoscopy (VB) is a new, noninvasive diagnostic technique which allows visualizing trachea and bronchi. Virtual images are created on the basis of data derived from helical CT scans using special protocol. A reconstructed, virtual image of the bronchial tree is very similar to that seen during conventional bronchofiberoscopy (FOB). The aim of the study was to compare VB images of the bronchi with those coming from FOB and evaluate diagnostic value of VB in centrally localized lung tumor.

MATERIAL AND METHODS

The studied group consisted of 40 patients with suspicion of centrally localized lung cancer. Primary diagnosis was based on the chest X-ray. Each patient underwent CT and bronchofiberoscopy and after those routine procedures the VB analysis was performed. The results of the FOB were not known for radiologist performing VB. In both used methods, FOB and VB, the evaluation and comparison of the features of tumor presence, bronchial stenosis and widening of the carina were performed. In all 40 patients lung cancer was confirmed. The diagnosis was established by histopathologic examination of the tissue biopsy: 32 patients (80%)--non small cell lung cancer, 2 patients (5%)--small cell lung cancer, 5 patients (12.5%)--squamous cell carcinoma, 1 patient (2.5%)--carcinoid.

RESULTS

Diagnostic value of VB in assessment of the for presence of the tumor in bronchus was: sensitivity 79.5%, specificity 95.5%, for bronchial stenosis: sensitivity 58.6%, specificity 98.1% and for widening of carina: sensitivity 60.7%, specificity 97.7%.

CONCLUSION

The results indicate that virtual bronchoscopy is highly sensitive and specific diagnostic method, a clinically valuable for the evaluation of lung tumor with a central location.

摘要

引言

虚拟支气管镜检查(VB)是一种新型的非侵入性诊断技术,可用于观察气管和支气管。虚拟图像是根据使用特殊协议从螺旋CT扫描获得的数据生成的。支气管树的重建虚拟图像与传统纤维支气管镜检查(FOB)所见的图像非常相似。本研究的目的是比较支气管的VB图像与FOB图像,并评估VB在中央型肺肿瘤中的诊断价值。

材料与方法

研究组由40例疑似中央型肺癌的患者组成。初步诊断基于胸部X线检查。每位患者均接受了CT和纤维支气管镜检查,在这些常规检查之后进行了VB分析。进行VB的放射科医生不知道FOB的结果。在FOB和VB这两种使用的方法中,均对肿瘤存在、支气管狭窄和隆突增宽的特征进行了评估和比较。40例患者均确诊为肺癌。诊断通过组织活检的组织病理学检查确定:32例患者(80%)——非小细胞肺癌,2例患者(5%)——小细胞肺癌,5例患者(12.5%)——鳞状细胞癌,1例患者(2.5%)——类癌。

结果

VB在评估支气管内肿瘤存在方面的诊断价值为:敏感性79.5%,特异性95.5%;对于支气管狭窄:敏感性58.6%,特异性98.1%;对于隆突增宽:敏感性60.7%,特异性97.7%。

结论

结果表明,虚拟支气管镜检查是一种高度敏感和特异的诊断方法,对评估中央型肺肿瘤具有临床价值。

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