Influence of endothelial cell protein C receptor on plasma clearance of factor VIIa.
作者信息
Gopalakrishnan R, Pendurthi U R, Hedner U, Agersø H, Esmon C T, Rao L V M
出版信息
J Thromb Haemost. 2012 May;10(5):971-3. doi: 10.1111/j.1538-7836.2012.04670.x.
Abstract
摘要
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Factor VIIa binding to endothelial cell protein C receptor: differences between mouse and human systems.因子 VIIa 与内皮细胞蛋白 C 受体的结合：鼠和人系统之间的差异。
Thromb Haemost. 2012 May;107(5):951-61. doi: 10.1160/TH11-09-0672. Epub 2012 Feb 28.
2
Factor X and factor VII binding to endothelial protein C receptor differs between species.凝血因子X和凝血因子VII与内皮细胞蛋白C受体的结合在不同物种之间存在差异。
J Thromb Haemost. 2011 Jun;9(6):1255-7. doi: 10.1111/j.1538-7836.2011.04295.x.
3
Clearance of rFVIIa and NN1731 after intravenous administration to Beagle dogs.静脉注射 rFVIIa 和 NN1731 后在比格犬体内的清除率。
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4
Recombinant human factor VIIa (rFVIIa) cleared principally by antithrombin following intravenous administration in hemophilia patients.静脉注射给予血友病患者后，重组人凝血因子 VIIa（rFVIIa）主要通过抗凝血酶清除。
J Thromb Haemost. 2011 Feb;9(2):333-8. doi: 10.1111/j.1538-7836.2010.04152.x.
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Endothelial cell protein C receptor cellular localization and trafficking: potential functional implications.内皮细胞蛋白C受体的细胞定位与转运：潜在的功能意义
Blood. 2009 Aug 27;114(9):1974-86. doi: 10.1182/blood-2009-03-208900. Epub 2009 Jul 8.
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7
Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity.因子VIIa与内皮细胞蛋白C受体的结合降低了其凝血活性。
J Thromb Haemost. 2007 Sep;5(9):1817-24. doi: 10.1111/j.1538-7836.2007.02648.x.
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Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium.内皮细胞蛋白C受体在内皮上作为凝血因子VIIa的细胞受体发挥作用。
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Multifunctional specificity of the protein C/activated protein C Gla domain.蛋白C/活化蛋白Cγ-羧基谷氨酸结构域的多功能特异性
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Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin.过表达内皮细胞蛋白C受体可改变止血平衡并保护小鼠免受内毒素侵害。
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