Effect of iron sources on the glycosylation macroheterogeneity of human recombinant IFN-γ produced by CHO cells during batch processes.
作者信息
Clincke Marie-Françoise, Guedon Emmanuel, Yen Frances T, Ogier Virginie, Goergen Jean-Louis
机构信息
Laboratoire Réactions et Génie des Procédés UPR-CNRS 3349, ENSAIA-INPL, Nancy-Université, 54505 Vandoeuvre-lès-Nancy, France ; Lipidomix (EA4422), ENSAIA-INPL, Nancy-Université, 54505 Vandoeuvre-lès-Nancy, France ; Genclis SAS, 54505 Vandoeuvre-lès-Nancy, France.
Laboratoire Réactions et Génie des Procédés UPR-CNRS 3349, ENSAIA-INPL, Nancy-Université, 54505 Vandoeuvre-lès-Nancy, France.
出版信息
BMC Proc. 2011 Nov 22;5 Suppl 8(Suppl 8):P114. doi: 10.1186/1753-6561-5-S8-P114. eCollection 2011.
Abstract
摘要
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Influence of intracellular nucleotide and nucleotide sugar contents on recombinant interferon-gamma glycosylation during batch and fed-batch cultures of CHO cells.
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