Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Brain Res. 2012 Oct 2;1476:119-31. doi: 10.1016/j.brainres.2012.01.062. Epub 2012 Feb 1.
This article is focused on understanding the mechanisms for the interactions between the central catecholamine (CA) and oxytocin (OXY) neurons and their relevance for brain function especially social behaviour in the field of pair bonding. Such a topic is analysed under two perspectives namely the intercellular communication modes between CA and OXT neurons and the molecular integrative mechanisms at the plasma membrane level between their respective decoding systems. As a matter of fact, recent observations strongly indicate a major role of volume transmission and receptor-receptor interactions in the CA/OXT neuron interplay in the brain control of social behaviour and pair bonding. This article is part of a Special Issue entitled: Brain Integration.
本文重点探讨了中枢儿茶酚胺（CA）和催产素（OXY）神经元相互作用的机制，及其在大脑功能，尤其是伴侣关系领域的社会行为中的相关性。从两个角度分析了这样一个主题，即 CA 和 OXT 神经元之间的细胞间通讯模式，以及它们各自解码系统在质膜水平上的分子整合机制。事实上，最近的观察结果强烈表明，在大脑对社会行为和伴侣关系的控制中，容积传递和受体-受体相互作用在 CA/OXT 神经元相互作用中起着重要作用。本文是特刊“大脑整合”的一部分。
