Güçlü Oya, Erkıran Murat, Aksu Emine Ebru, Aksu Haluk
Bakırköy Mental Health, Neurology and Neurosurgery Hospital 9, Psychiatry, Kayseri.
Turk Psikiyatri Derg. 2012 Spring;23(1):1-8.
The aim of this study is to investigate the social anxiety disorder comorbidity and clinical features in schizophrenia.
102 (23 women and 79 men) outpatients who had been followed in the Psychotic Disorders Unit in Bakırköy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery were diagnosed with schizophrenia according to DSM-IV criteria were included in the study. Schizophrenia and Social anxiety disorder were assessed by a structured clinical interview for DSM-IV. Patients were evaluated with a questionnaire which included demographics, clinical characteristics, Liebowitz social anxiety scale, Positive and Negative Syndrome Scale (PANSS), Calgary depression scale for schizophrenia (CDSS),The Scale of Unawareness of Mental Disorders (SUMD), Short form-36 health survey questionnaire and state-trait anxiety ınventory.
In remission, 22 patients (21.6%) had co-morbid social anxiety disorder. Patients with social anxiety disorder comorbidity, had higher levels of awareness. Their depression scores were higher and functional impairments were lower. These patients had been treated with typical and atypical antipsychotics and antidepressants.
Social anxiety disorder comorbidity in schizophrenia adversely affects the quality of life and is not rare. Future studies should be planned with the assesment of social anxiety disorder treatment as well as schizophrenia treatment.
本研究旨在调查精神分裂症患者中社交焦虑障碍的共病情况及临床特征。
选取在巴基尔柯伊精神病学、神经病学和神经外科研究与培训医院的精神病科病房接受随访的102名门诊患者(23名女性和79名男性),这些患者根据《精神疾病诊断与统计手册》第四版(DSM-IV)标准被诊断为精神分裂症,纳入本研究。采用针对DSM-IV的结构化临床访谈对精神分裂症和社交焦虑障碍进行评估。使用一份问卷对患者进行评估,问卷内容包括人口统计学信息、临床特征、利博维茨社交焦虑量表、阳性与阴性症状量表(PANSS)、精神分裂症卡尔加里抑郁量表(CDSS)、精神障碍自知力量表(SUMD)、简明健康调查量表(Short form-36)以及状态-特质焦虑问卷。
在病情缓解期,22名患者(21.6%)患有共病社交焦虑障碍。共病社交焦虑障碍的患者自知力水平较高。他们的抑郁得分较高,功能损害较低。这些患者接受了典型和非典型抗精神病药物以及抗抑郁药物治疗。
精神分裂症中共病社交焦虑障碍对生活质量有不利影响,且并不罕见。未来的研究应计划评估社交焦虑障碍的治疗以及精神分裂症的治疗。