Mazeh Doron, Bodner Ehud, Weizman Ronit, Delayahu Yael, Cholostoy Alexander, Martin Tatiana, Barak Yoram
Abarbanel Mental Health Centre, Bar-Ilan University, Israel.
Int J Soc Psychiatry. 2009 May;55(3):198-202. doi: 10.1177/0020764008093447.
The co-morbid occurrence of anxiety disorders and schizophrenia has recently begun to be investigated. Social anxiety may be especially important to diagnose and manage among patients with schizophrenia.
To investigate the prevalence and correlates of social phobia in patients with schizophrenia.
Diagnosis of schizophrenia and schizoaffective disorders as well as co-morbid anxiety disorders was established according to DSM-IV and the Structured Clinical Interview for Diagnosis (SCID-P Hebrew version). Severity of psychotic symptoms and social anxiety symptoms was assessed with the Positive and Negative Symptom Scale (PANSS) and the Liebowitz Social Anxiety Scale (LSAS).
The cohort studied included 117 patients with schizophrenia. Thirteen patients were diagnosed as suffering from co-morbid social phobia (11%). There was a tendency for patients with co-morbid social phobia to have higher severity PANSS total score. There was a significant correlation between the score of the LSAS ;fear' and PANSS positive subscales. Avoidance scores were higher among patients with negative signs.
Co-morbidity of schizophrenia and social anxiety disorder is not rare among patients with schizophrenia. Treatment implications need be further investigated.
焦虑症与精神分裂症的共病现象近来已开始受到研究。社交焦虑对于精神分裂症患者的诊断和管理可能尤为重要。
调查精神分裂症患者中社交恐惧症的患病率及其相关因素。
依据《精神疾病诊断与统计手册》第四版(DSM-IV)以及诊断用结构化临床访谈(SCID-P希伯来语版)对精神分裂症、分裂情感性障碍以及共病的焦虑症进行诊断。使用阳性与阴性症状量表(PANSS)和利博维茨社交焦虑量表(LSAS)评估精神病性症状和社交焦虑症状的严重程度。
所研究的队列包括117名精神分裂症患者。13名患者被诊断为共病社交恐惧症(11%)。共病社交恐惧症的患者有PANSS总分严重程度更高的倾向。LSAS“恐惧”得分与PANSS阳性分量表之间存在显著相关性。阴性症状患者的回避得分更高。
精神分裂症患者中精神分裂症与社交焦虑障碍的共病并不罕见。治疗意义有待进一步研究。