缺血再灌注：移植手术中不可避免的阶段
[Ischemia reperfusion: an unavoidable phase of transplant procedures].
作者信息
Hauet Thierry, Thuillier Raphaël, Tillement Jean Paul
机构信息
INSERM U927, 6 rue de la Milétrie, BP 199, Poitiers 86034, INRA, Plateforme IBISA, Chirurgie-Expérimentale-Transplantation, Domaine du Magneraud, Surgères, Biochimie, Pole UBM, CHU Poitiers 86000.
出版信息
Bull Acad Natl Med. 2011 Apr-May;195(4-5):831-42; discussion 842-5.
Transplanted organs are inevitably exposed to ischemia-reperfusion injury. Cold preservation is also used to reduced metabolic processes during ex vivo transport but triggers a complex pathophysiological syndrome which is responsible for delayed graft function after reperfusion. Ischemia-reperfusion injury is also associated with chronic graft dysfunction.
移植器官不可避免地会遭受缺血再灌注损伤。低温保存也用于在离体运输过程中降低代谢过程，但会引发一种复杂的病理生理综合征，这是再灌注后移植器官功能延迟的原因。缺血再灌注损伤还与慢性移植器官功能障碍有关。
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