Department of Dermatology, Shimane University Faculty of Medicine, Shimane, Japan.
Allergol Int. 2012 Mar;61(1):101-5. doi: 10.2332/allergolint.11-OA-0345.
Wheat is one of the most common causes of food allergies. The exact prevalence of wheat allergy has not been well delineated in Japanese adults.
We enrolled 935 adults in a cohort study established by Shimane University in order to examine the determinants of lifestyle-related diseases. A screening was conducted by a questionnaire-based examination and a detection of serum omega-5 gliadin-specific IgE. Subjects who tested positive in the questionnaire-based examination and/or the serum omega-5 gliadin-specific IgE test were further examined by detailed interviews and skin prick tests.
A total of 22 subjects were picked up by the screening process, and 17 of these were further examined by secondary testing. Only two subjects were conclusively identified as having wheat allergy.
The prevalence of wheat allergy in Japanese adults was found to be 0.21% by using a combination of questionnaire-based examination, skin prick test and serum omega-5 gliadin-specific IgE test.
小麦是食物过敏的最常见原因之一。在日本成年人中，尚未明确界定小麦过敏的具体患病率。
我们招募了 935 名成年人参加由岛根大学建立的队列研究，以研究与生活方式相关疾病的决定因素。通过基于问卷的检查和血清 ω-5 麦醇溶蛋白特异性 IgE 的检测进行筛查。在基于问卷的检查和/或血清 ω-5 麦醇溶蛋白特异性 IgE 检测中呈阳性的受试者通过详细的访谈和皮肤点刺试验进一步检查。
筛选过程共发现 22 例，其中 17 例通过二次检测进一步检查。只有两名患者被确认为患有小麦过敏症。
通过使用基于问卷的检查、皮肤点刺试验和血清 ω-5 麦醇溶蛋白特异性 IgE 试验的组合，发现日本成年人的小麦过敏患病率为 0.21%。
