乳房切除术后疼痛综合征：发生率和风险。
Post-mastectomy pain syndrome: incidence and risks.
机构信息
Federal University of Rio de Janeiro State and National Cancer Institute, Rio de Janeiro, Brazil.
出版信息
Breast. 2012 Jun;21(3):321-5. doi: 10.1016/j.breast.2012.01.019. Epub 2012 Feb 27.
BACKGROUND
Post-mastectomy pain syndrome is defined as a chronic pain that persists beyond the normal healing time of 3 months. It is considered a neuropathic condition that arises after surgery for breast cancer.
AIM
To evaluate the incidence and risk factors of pain syndromes in patients undergoing surgical treatment of breast cancer in the National Cancer Institute.
METHODS
This study is a prospective cohort of women undergoing surgical treatment for breast cancer from September 2008 to June 2009, followed up until 6 months postoperatively.
RESULTS AND CONCLUSIONS
One hundred seventy-four women were examined. The mean age was 58 years. The incidence of pain syndrome was 52%. Younger women (<40 years) and those who were submitted to axillary lymph node dissection (with more than 15 lymph nodes excised) have shown a significantly increased risk of pain syndrome after surgery for breast cancer (relative risk (RR) =5.23 95% confidence interval (CI): 1.11-24.64) and (RR=2.01 95% CI: 1.08-3.75).
背景
乳腺癌根治术后疼痛综合征是指一种持续时间超过正常 3 个月愈合期的慢性疼痛。它被认为是一种在乳腺癌手术后出现的神经病理性疾病。
目的
评估国立癌症研究所行乳腺癌手术患者疼痛综合征的发生率和风险因素。
方法
这是一项对 2008 年 9 月至 2009 年 6 月间行乳腺癌手术的女性进行的前瞻性队列研究，随访至术后 6 个月。
结果与结论
共检查了 174 名女性。平均年龄为 58 岁。疼痛综合征的发生率为 52%。年轻女性（<40 岁）和接受腋窝淋巴结清扫术（切除超过 15 个淋巴结）的女性在乳腺癌手术后发生疼痛综合征的风险显著增加（RR=5.23，95%CI：1.11-24.64）和（RR=2.01，95%CI：1.08-3.75）。
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