Martin Juan Jose
Stroke Unit Sanatorio Allende, Cordoba, Argentina.
Front Neurol Neurosci. 2012;30:46-9. doi: 10.1159/000333405. Epub 2012 Feb 14.
Delirium is one of the most serious and common complications that up to one third of older patients admitted to hospital develop. It is characterized by a disturbance of consciousness, decreased attention, and disorganized thinking that develops over a short period of time, and fluctuates during the course of the day. Delirium post-stroke prevalence ranges from 13 to 48% in general hospitals, and from 10.1 to 28% in Stroke Units. The Confusion Assessment Method and the Delirium Rating Scale are used as delirium screening tools. The cause of delirium is likely to be multifactorial. In stroke, reduced perfusion of the brain with hypoxia, which deranges neurotransmission, may be the cause. Delirium is more frequent after intracerebral hemorrhage and infarction in specific brain areas. Delirium without other signs of stroke has been reported more often after right-sided than after left-sided lesions. Age, cognitive decline, and multiple coexisting conditions are the most consistent and important risk factors for delirium post-stroke. Haloperidol is currently used as the drug of choice, if sedation is needed.
谵妄是最严重且常见的并发症之一,高达三分之一的老年住院患者会出现该症状。其特征为意识障碍、注意力下降以及思维紊乱,这些症状在短时间内出现,并在一天中波动变化。在综合医院,卒中后谵妄的患病率为13%至48%,在卒中单元则为10.1%至28%。混乱评估方法和谵妄评定量表被用作谵妄筛查工具。谵妄的病因可能是多因素的。在卒中中,大脑灌注减少伴缺氧,这会扰乱神经传递,可能是病因所在。在特定脑区发生脑出血和梗死之后,谵妄更为常见。据报道,在无其他卒中体征的情况下,右侧病变后出现谵妄的情况比左侧病变后更为频繁。年龄、认知衰退以及多种并存疾病是卒中后谵妄最一致且重要的危险因素。如果需要镇静,目前氟哌啶醇被用作首选药物。