McManus John, Pathansali Rohan, Stewart Rob, Macdonald Alastair, Jackson Stephen
Department of Clinical Gerontology, Clinical Age Research Unit, King's College Hospital NHS Foundation Trust, Denmark Hill, Bessemer Road, London SE5 9PJ, UK.
Age Ageing. 2007 Nov;36(6):613-8. doi: 10.1093/ageing/afm140. Epub 2007 Oct 25.
Delirium is not only one of the most common complications that older patients develop after admission to hospital but it is also one of the most serious. Although stroke is a known predisposing factor for delirium, few studies have investigated this association and results from existing studies give conflicting results with prevalence estimates ranging from 13 to 48%. The aetiology of delirium post-stroke is poorly understood. There is no consensus on the best screening tool to use to detect delirium in the post-stroke setting. Specific stroke types may be more likely to precipitate delirium than others, for example, delirium is more frequent after intracerebral haemorrhage and total anterior circulation infarction (TACI). In addition, case reports have suggested that delirium may be associated with specific lesions, for example, in the thalamus and caudate nucleus. There is a lack of intervention data in both the prevention and treatment of delirium post-stroke. However, it is known that the development of delirium post-stroke has grave prognostic implications. It is associated with longer stay in hospital, increased mortality and increased risk of institutionalisation post discharge. In this article, we review the literature to date on delirium in the acute stroke setting.
谵妄不仅是老年患者入院后最常见的并发症之一,也是最严重的并发症之一。虽然中风是已知的谵妄诱发因素,但很少有研究调查这种关联,现有研究的结果相互矛盾,患病率估计在13%至48%之间。中风后谵妄的病因尚不清楚。对于在中风后环境中检测谵妄的最佳筛查工具,目前尚无共识。特定类型的中风可能比其他类型更容易引发谵妄,例如,脑出血和完全前循环梗死(TACI)后谵妄更为常见。此外,病例报告表明,谵妄可能与特定病变有关,例如丘脑和尾状核的病变。在中风后谵妄的预防和治疗方面,缺乏干预数据。然而,众所周知,中风后谵妄的发生具有严重的预后意义。它与住院时间延长、死亡率增加以及出院后入住机构的风险增加有关。在本文中,我们回顾了迄今为止关于急性中风环境中谵妄的文献。