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移植受者的光保护

Photoprotection in transplant recipients.

作者信息

Surber Christian, Pittelkow Mark, Lautenschlager Stephan

机构信息

Department of Dermatology, University Hospital Basel, Petersgraben 4, Basel, Switzerland.

出版信息

Curr Probl Dermatol. 2012;43:171-96. doi: 10.1159/000335799. Epub 2012 Feb 17.

Abstract

Skin cancers remain the most commonly diagnosed neoplasms among organ transplant recipients (OTRs), comprising nearly 40% of all posttransplant malignancies. The occurrence of skin tumors has a considerable impact on the quality of life and the overall survival of OTRs. Ultraviolet radiation (UVR) is the major environmental cause of nonmelanoma skin cancers, and it is therefore pivotal to protect the skin from UVR in order to prevent de novo and progression of preinvasive and invasive malignancies. The present chapter delivers background information on UVR, photoprotection and accompanying concerns regarding vitamin D, as well as educational and behavioral aspects of photoprotection in OTRs; some common misconceptions and mistakes regarding photoprotection are addressed as well.

摘要

皮肤癌仍然是器官移植受者(OTR)中最常被诊断出的肿瘤,占所有移植后恶性肿瘤的近40%。皮肤肿瘤的发生对OTR的生活质量和总体生存率有相当大的影响。紫外线辐射(UVR)是非黑色素瘤皮肤癌的主要环境致病因素,因此保护皮肤免受UVR照射对于预防原位以及侵袭前和侵袭性恶性肿瘤的发生和进展至关重要。本章提供了有关UVR、光防护以及与维生素D相关的问题的背景信息,以及OTR光防护的教育和行为方面的内容;还讨论了一些关于光防护的常见误解和错误。

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