Gauvain Karen M, Durham Benjamin H, McHugh Michele, Geller Thomas J
Division of Pediatric Hematology/Oncology, St Louis University School of Medicine/Cardinal Glennon Children's Hospital, Bob Costas Cancer Center, St Louis, MO 63104, USA.
J Child Neurol. 2012 Dec;27(12):1597-601. doi: 10.1177/0883073812436878. Epub 2012 Feb 28.
Atypical teratoid/rhabdoid tumor is a rare, highly malignant central nervous system tumor most commonly occurring in very young children. Atypical teratoid/rhabdoid tumor most often presents as an expanding mass with symptoms consistent with the location of the tumor and may present with metastatic leptomeningeal disease. The authors describe 2 cases of rapidly progressive, diffuse leptomeningeal atypical teratoid/rhabdoid tumor without a solid primary mass. These cases demonstrate a clinical picture that can easily be confused with a basilar meningitis, encephalomyelitis, or vasculitis.
非典型畸胎样/横纹肌样瘤是一种罕见的、高度恶性的中枢神经系统肿瘤，最常发生于幼儿。非典型畸胎样/横纹肌样瘤最常表现为占位性肿块，其症状与肿瘤位置相符，也可能表现为软脑膜转移疾病。作者描述了2例快速进展的弥漫性软脑膜非典型畸胎样/横纹肌样瘤，无实体原发肿块。这些病例呈现出一种临床症状，很容易与基底脑膜炎、脑脊髓炎或血管炎相混淆。
