Frenay J J, Groen J J, Endtz L J
Clin Neurol Neurosurg. 1979;81(1):13-25. doi: 10.1016/s0303-8467(79)80003-7.
On the basis of six cases of a tumour at the spinocranial junction, the clinical symptomatology is discussed with special reference to the occurrence of astereognosis and amyotrophy of the hand muscles. Possible mechanisms underlying these symptoms are discussed. In the authors' opinion, the frequent association of these symptoms is explained by the association of two pathogenic mechanisms, i.e., compression of the posterior column or interference with the arterial blood flow to the medial lemniscus, leading to astereognosis, and interference with the venous blood flow, leading to amyotrophy of the hand muscles.
基于6例颅颈交界处肿瘤的病例，对临床症状进行了讨论，特别提及了手部肌肉实体觉丧失和肌萎缩的发生情况。探讨了这些症状背后可能的机制。作者认为，这些症状频繁同时出现是由两种致病机制共同作用所致，即后柱受压或内侧丘系动脉血流受到干扰导致实体觉丧失，以及静脉血流受到干扰导致手部肌肉萎缩。
