Konefał Halina, Peregud-Pogorzelski Jarosław, Hnatyszyn Grazyna, Posio Viloetta, Stepaniuk Maria, Kram Andrzej, Czeszyńska Maria Beata
Department of Neonatology, Pomeranian Medical University, Szczecin, Poland.
Ginekol Pol. 2011 Sep;82(9):705-8.
The first case of a female neonate born from an in vitro fertilization with embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI) (IVF-ET (ICSI) with two histologically different tumours (craniopharyngioma and hepatoblastoma) is described. Anti-neoplasmatic therapy was abandoned due to the significant extent of the disease (craniopharyngioma, 15 x 12 cm in diameter with active internal hydrocephalus; and right liver lobe hepatoblastoma, 5 cm in diameter) and the severely impaired general condition of the neonate. The neonate died on the 30th day of life due to cerebellar and brainstem herniation, followed by circulatory and respiratory failure.
本文描述了首例通过体外受精胚胎移植（IVF-ET）和卵胞浆内单精子注射（ICSI）（IVF-ET（ICSI））出生的女性新生儿，其患有两种组织学上不同的肿瘤（颅咽管瘤和成肝细胞瘤）。由于疾病范围广泛（颅咽管瘤，直径15×12 cm，伴有活动性内部脑积水；右肝叶成肝细胞瘤，直径5 cm）以及新生儿的一般状况严重受损，放弃了抗肿瘤治疗。该新生儿在出生后第30天因小脑和脑干疝出，继而出现循环和呼吸衰竭而死亡。
