Jia Liangyuan, Weng Junjie, Zhou Zhongyue, Qi Fei, Guo Wenyue, Zhao Lianming, Chen Juan
National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei, Anhui 230029, People's Republic of China.
Rev Sci Instrum. 2012 Feb;83(2):026105. doi: 10.1063/1.3685251.
In this work, we coupled synchrotron vacuum ultraviolet photoionization (SVUV PI) method with the laser-induced acoustic desorption (LIAD) technique for mass spectrometric analysis. The LIAD technique is a "soft" desorption method, which could avoid the degradation of analytes during desorption process. Meanwhile, SVUV PI is an efficient "soft" ionization source. The new combination of the "soft" desorption technique and "soft" photoionization method is well suitable to reduce the difficulty for interpreting the mass spectra of the fragile compounds and heavy oils.