Batta A G, Engen D E, Reiman H M, Winkelmann R K
Department of Urology, Mayo Clinic, Rochester, Minnesota.
Urology. 1990 Nov;36(5):457-64. doi: 10.1016/s0090-4295(90)80298-2.
Condyloma acuminatum is a common form of venereal disease. Most patients with condylomata acuminata suffer from only the local cosmetic and irritative effects of the lesions. Few patients have progression to aggressive, regionally distributed lesions that can be life-threatening. We describe a forty-three-year-old white woman who had a seventeen-year history of scleroderma with extravesical and intravesical condylomata acuminata. During two years of conservative management with transurethral excision, electrocoagulation, and intravesical chemotherapy, the disease progressed to involve the entire bladder and resulted in obstructive renal insufficiency that required anterior exenteration and urinary diversion. The natural history of the disease is described, and the relevant literature is reviewed.
尖锐湿疣是一种常见的性病形式。大多数尖锐湿疣患者仅遭受病变的局部美容和刺激影响。少数患者会进展为侵袭性、区域性分布的病变，可能危及生命。我们描述了一位43岁的白人女性，她有17年的硬皮病病史，伴有膀胱外和膀胱内尖锐湿疣。在经尿道切除、电凝和膀胱内化疗的两年保守治疗期间，疾病进展至累及整个膀胱，并导致梗阻性肾功能不全，需要进行前盆腔脏器清除术和尿流改道。本文描述了该疾病的自然病程，并对相关文献进行了综述。
