[Laser irradiation: study of general and local mechanisms of its action in irradiation of the eyeball. An experimental study. 3].

Rabbit ocular tissues, brain, and blood were examined before and after irradiation of the eyeball with He-Ne laser. Scanning electron microscopy, radioimmunoassay, and biochemical methods were employed in the study. The findings evidence that irradiation of the eyeball results in reduced lipid peroxidation activity and elevated antiradical defense enzymes activity not only in ocular tissues but in the corresponding brain hemisphere and blood, which fact appears to be due to direct effect of laser radiation on the blood and brain via the optic nerve that may be a light conductor for a certain wavelength. Local increase of the eyeball corneal permeability in laser irradiation may be explained by activation of membrane phospholipases, combined with electrolyte shifts; morphologically and functionally it manifests by changed endotheliocyte stereotopography.