Kiselev G A, Lebedev O I, Gusev S A, Povaliĭ T M, Pospelov T M, Lukoshkin A V, Mal'kov P G
Vestn Oftalmol. 1990 Jul-Aug;106(4):59-63.
Rabbit ocular tissues, brain, and blood were examined before and after irradiation of the eyeball with He-Ne laser. Scanning electron microscopy, radioimmunoassay, and biochemical methods were employed in the study. The findings evidence that irradiation of the eyeball results in reduced lipid peroxidation activity and elevated antiradical defense enzymes activity not only in ocular tissues but in the corresponding brain hemisphere and blood, which fact appears to be due to direct effect of laser radiation on the blood and brain via the optic nerve that may be a light conductor for a certain wavelength. Local increase of the eyeball corneal permeability in laser irradiation may be explained by activation of membrane phospholipases, combined with electrolyte shifts; morphologically and functionally it manifests by changed endotheliocyte stereotopography.
在用氦氖激光照射兔眼球前后，对其眼组织、脑和血液进行了检查。本研究采用了扫描电子显微镜、放射免疫测定法和生化方法。研究结果表明，照射眼球不仅会导致眼组织中脂质过氧化活性降低和抗自由基防御酶活性升高，而且相应的脑半球和血液中也会出现这种情况，这一事实似乎是由于激光辐射通过视神经对血液和大脑产生直接影响，视神经可能是特定波长的光导体。激光照射时眼球角膜通透性的局部增加可能是由于膜磷脂酶的激活以及电解质转移所致；在形态和功能上，它表现为内皮细胞立体定位的改变。
