Gutaj Paweł, Wender-Ozegowska Ewa, Mantaj Urszula, Zawiejska Agnieszka, Brazert Jacek
Klinika Połoznictwa i Chorób Kobiecych, Katedra Ginekologii, Poloinictwa i Onkologii Ginekologicznej, Uniwersytet Medyczny im. K. Marcinkowskiego, Poznań, Polska.
Ginekol Pol. 2011 Nov;82(11):827-33.
Maternal overweight and obesity constitute the most important factors causing perinatal complications. The purpose of the study was to analyze obstetrical results in overweight/obese pregnant women with gestational diabetes in relation to Institute of Health recommendations concerning gestational weight gain and assessment of the role of prepregnancy BMI in prediction of macrosomia, pregnancy induced hypertension and cesarean deliveries.
Retrospective analysis of 209 overweight and obese pregnant women with gestational diabetes divided into 4 subgroups according to The National Institute of Health (USA) recommendations. The following data were included in the analysis: gestational week in which GDM was diagnosed; HbA1c level in the first and third trimester just before delivery; incidence of pregnancy induced hypertension; incidence of cesarean deliveries; incidence of macrosomia. The following data of II, III, IV subgroups were compared to these found in I subgroup which was classified as the control group. Selected obstetric parameters were also compared between subgroups II, III, IV RESULTS: The selected parameters of subgroups II, III, IV were not significantly different from these of subgroup I. Pregnancy induced hypertension was diagnosed more frequently among subgroup II in comparison to subgroup III. Using ROC curves analysis, the role of pre-pregnancy BMI was found in the prognosis of: birth weight greater than 4300 g, pregnancy induced hypertension, cesarean delivery
孕产妇超重和肥胖是导致围产期并发症的最重要因素。本研究旨在分析患有妊娠期糖尿病的超重/肥胖孕妇的产科结局,这些结局与美国国立卫生研究院关于孕期体重增加的建议相关,并评估孕前体重指数在预测巨大儿、妊娠期高血压和剖宫产方面的作用。
对209例患有妊娠期糖尿病的超重和肥胖孕妇进行回顾性分析,根据美国国立卫生研究院的建议将其分为4个亚组。分析中纳入了以下数据:诊断妊娠期糖尿病时的孕周;分娩前第一和第三孕期的糖化血红蛋白水平;妊娠期高血压的发生率;剖宫产的发生率;巨大儿的发生率。将第二、三、四亚组的以下数据与被归类为对照组的第一亚组的数据进行比较。还对第二、三、四亚组之间的选定产科参数进行了比较。结果:第二、三、四亚组的选定参数与第一亚组的参数无显著差异。与第三亚组相比,第二亚组中妊娠期高血压的诊断更为频繁。使用ROC曲线分析,发现孕前体重指数在以下预后方面有作用:出生体重超过4300克、妊娠期高血压、剖宫产。