Suppr超能文献

[脉络膜黑色素瘤的内切除治疗]

[Choroidal melanoma treatment by endoresection].

作者信息

Stopa Marcin, Kociecki Jarosław, Rospond-Kubiak Iwona, Rakowicz Piotr

机构信息

Z Katedry i Kliniki Okulistyki Uniwersytetu Medycznego w Poznaniu.

出版信息

Klin Oczna. 2011;113(10-12):367-72.

Abstract

PURPOSE

To report choroidal melanoma treatment by endoresection.

MATERIAL AND METHODS

A retrospective review of a series of 2 patients with choroidal melanoma that did not meet the criteria for brachytherapy. Both patients were treated by tumor endoresection supported by brachytherapy. Outcome measures included preoperative and postoperative visual acuity at 1, 3, 6 months. Preoperative evaluation included tumor measurements in ultrasound. Systemic evaluation (liver function test, chest x ray, abdominal ultrasound), was carried out to monitor possible metastases in the observation period.

RESULTS

The two operated patients were followed-up for 6 months. Visual acuity deteriorated from 5/16 (0.51 logMAR) preoperatively to 5/25 (0.7 logMAR) postoperatively in patient 1, and improved from 3/50 (1.22 logMAR) do 5/25 (0.7 logMAR) in patient 2. This corresponded to deterioration by 0.19 logMAR and improvement by 0.52 logMAR respectively. Neither tumor recurrence nor metastases were detected in the follow-up period.

CONCLUSIONS

Endoresection is a treatment option, alternative to enucleation, that can conserve the eye It sometimes can be performed in eyes that are not eligible for trans-scleral resection. Further larger studies are needed to establish the efficacy of this still controversial surgery.

摘要

目的

报告脉络膜黑色素瘤的眼内切除术治疗情况。

材料与方法

回顾性分析2例不符合近距离放疗标准的脉络膜黑色素瘤患者。2例患者均接受了在近距离放疗支持下的肿瘤眼内切除术。观察指标包括术后1、3、6个月时的术前和术后视力。术前评估包括超声测量肿瘤大小。进行全身评估(肝功能检查、胸部X线、腹部超声)以监测观察期内可能的转移情况。

结果

2例手术患者均随访6个月。患者1的视力从术前的5/16(0.51 logMAR)降至术后的5/25(0.7 logMAR),患者2的视力从3/50(1.22 logMAR)提高到5/25(0.7 logMAR)。这分别相当于视力下降0.19 logMAR和提高0.52 logMAR。随访期间未发现肿瘤复发或转移。

结论

眼内切除术是一种可替代眼球摘除术的治疗选择,能够保留眼球。有时可在不符合经巩膜切除术条件的眼中进行。需要进一步开展更大规模的研究来确定这种仍存在争议的手术的疗效。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验