Simicević Darja Sodec, Lovrencić-Huzjan Arijana, Trifunović-Macek Zvjezdana, Vuković-Ogrizek Martina, Strineka Maja, Martinić-Popović Irena, Demarin Vida
University Department of Neurology, Referral Center for Neurovascular Disorders of the Ministry of Health of the Republic of Croatia.
Acta Clin Croat. 2011 Sep;50(3):323-8.
Hemodynamic changes can be noninvasively real-time monitored in stroke patients by means of transcranial Doppler sonography (TCD). The aim of this pilot study was to assess hemodynamic changes in both middle cerebral arteries (MCA) in aphasic stroke patients by means of TCD during verbal stimulation. Eight aphasic patients with stroke in the territory of the left MCA were tested by modified Boston Diagnostic Aphasia Examination (BDAE) within 3 days of stroke onset. Both MCA were monitored simultaneously by means of TCD with 2 MHz probes. Basic MCA mean blood flow velocity (MBFV) values were assessed and monitored during verbal stimulation. Verbal stimulation was performed with 30 photos of objects for daily usage, arranged by function. The same test was performed in 16 right-handed healthy controls. In stroke patients, the mean MBFV were 56 cm/s in the left MCA and 56 cm/s in the right MCA. A mean 30% increase was observed in the left MCA and 22% in the right MCA. In healthy controls, a mean 21.7% increase was observed in the left MCA and 18% in the right MCA. A trend toward higher percentage of MBFV increase was observed in the left MCA during verbal stimulations in aphasic patients as compared to control subjects.
通过经颅多普勒超声（TCD）可以对中风患者的血流动力学变化进行无创实时监测。这项初步研究的目的是通过TCD评估失语性中风患者在言语刺激期间双侧大脑中动脉（MCA）的血流动力学变化。8例左侧大脑中动脉供血区中风的失语患者在中风发作后3天内接受了改良波士顿失语症诊断检查（BDAE）。使用2MHz探头通过TCD同时监测双侧大脑中动脉。在言语刺激期间评估并监测大脑中动脉平均血流速度（MBFV）的基础值。使用30张按功能排列的日常用品照片进行言语刺激。对16名右利手健康对照者进行了相同的测试。在中风患者中，左侧大脑中动脉的平均MBFV为56cm/s，右侧大脑中动脉为56cm/s。左侧大脑中动脉平均增加30%，右侧大脑中动脉增加22%。在健康对照者中，左侧大脑中动脉平均增加21.7%，右侧大脑中动脉增加18%。与对照受试者相比，在失语患者言语刺激期间，左侧大脑中动脉MBFV增加的百分比有更高的趋势。
