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用于阿尔茨海默病诊断的药物捕获与递送

Drug trapping and delivery for Alzheimer's diagnosis.

作者信息

Jalil M A, Kamoldilok Surachart, Saktioto T, Ong C T, Yupapin Preecha P

机构信息

Ibnu Sina Institute of Fundamental Science Studies, Nanotechnology Research Alliance,Universiti Teknologi Malaysia (UTM), Johor Bahru, Malaysia.

出版信息

Artif Cells Blood Substit Immobil Biotechnol. 2012 Oct;40(5):303-8. doi: 10.3109/10731199.2012.657203. Epub 2012 Mar 2.

Abstract

In this investigation, a new design based on a PANDA ring resonator as an optical trapping tool for tangle protein, molecular motor storage, and delivery is proposed. The optical vortices are generated and the trapping mechanism is controlled in the same way as the conventional optical tweezers. The trapping force is produced by a combination of the gradient field and scattering photons. The required molecular volume is trapped and moved dynamically within the molecular network. The tangle protein and molecular motor can be transported and delivered to the required destinations for Alzheimer's diagnosis by molecular buffer and bus network.

摘要

在本研究中,提出了一种基于熊猫环形谐振器的新设计,作为用于缠结蛋白、分子马达存储和输送的光捕获工具。以与传统光镊相同的方式产生光学涡旋并控制捕获机制。捕获力由梯度场和散射光子共同产生。所需的分子体积在分子网络内被动态捕获和移动。缠结蛋白和分子马达可通过分子缓冲器和总线网络被运输并输送到用于阿尔茨海默病诊断的所需目的地。

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