Agroprocessing and Natural Products Division, National Institute for Interdisciplinary Science and Technology (CSIR), Thiruvananthapuram, Kerala, India.
Int J Food Sci Nutr. 2012 Nov;63(7):832-4. doi: 10.3109/09637486.2011.607156. Epub 2012 Mar 5.
Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than the reference standard drug acarbose. Drying of rhizomes was found to enhance α-glucosidase (IC₅₀ = 1.32-0.38 μg/ml) and α-amylase (IC₅₀ = 64.7-34.3 μg/ml) inhibitory capacities of volatile oils. Ar-Turmerone, the major volatile component in the rhizome also showed potent α-glucosidase (IC₅₀ = 0.28 μg) and α-amylase (IC₅₀ = 24.5 μg) inhibition.
姜黄挥发油抑制葡萄糖苷酶活性的抗糖尿病能力进行了评价。与对照标准药物阿卡波糖相比，姜黄挥发油更能有效地抑制葡萄糖苷酶。研究发现，根茎的干燥增强了挥发油的α-葡萄糖苷酶（IC₅₀ = 1.32-0.38 μg/ml）和α-淀粉酶（IC₅₀ = 64.7-34.3 μg/ml）抑制能力。芳姜酮是根茎中的主要挥发性成分，也表现出很强的α-葡萄糖苷酶（IC₅₀ = 0.28 μg）和α-淀粉酶（IC₅₀ = 24.5 μg）抑制活性。
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