Wisbeck Jacob M, Parks Brent G, Schon Lew C
Department of Orthopaedics, Union Memorial Hospital, Baltimore, Maryland, USA.
Orthopedics. 2012 Mar 7;35(3):e331-4. doi: 10.3928/01477447-20120222-41.
Standard 4-strand repair of Achilles tendon tears is effective, but additional strength may be desirable in patients who are compromised or those with reruptures. Use of a xenograft scaffold has not been investigated biomechanically in Achilles tendon repair. This study compared stiffness, gap formation, and ultimate load to failure with Krackow repair vs Krackow repair augmented with xenograft scaffold in 6 matched pairs of fresh-frozen human lower extremities. The Achilles tendon was transected 4 cm above the calcaneal insertion. Specimens were randomized to receive standard Krackow repair or Krackow repair augmented with a porcine xenograft scaffold. The graft was wrapped around the repaired tendon, sutured to itself with 2-0 FiberWire (Arthrex, Naples, Florida), and attached to the tendon distally and proximally and then medially and laterally. Specimens were loaded for 200 cycles between 5 and 30 N. Load to 5-mm gapping and load to ultimate failure were measured. Xenograft scaffold augmentation of standard Krakow Achilles tendon repair was significantly stronger and stiffer than standard Krackow repair in a biomechanical model immediately after repair (39.0±8.8 vs 24.4±4.6 N/mm; P=.01). The augmented repair group had significantly higher load to ultimate failure than did the Krackow group (862.7±174.0 vs 479.5±65.5 N; P<.01). Biological factors remain to be investigated, but this augmentation method could provide additional strength in patients who are compromised or those with reruptures.
跟腱撕裂的标准四股修复方法是有效的,但对于身体状况不佳或有再断裂的患者,可能需要额外的强度。在跟腱修复中,尚未对异种移植支架进行生物力学研究。本研究比较了6对新鲜冷冻的人体下肢中,采用Krackow修复法与采用异种移植支架增强的Krackow修复法在刚度、间隙形成和极限破坏载荷方面的差异。跟腱在跟骨附着点上方4厘米处横断。标本随机接受标准Krackow修复或用猪异种移植支架增强的Krackow修复。移植物包裹在修复后的肌腱周围,用2-0 FiberWire(Arthrex公司,佛罗里达州那不勒斯)自身缝合,并在肌腱的远端、近端以及内侧和外侧进行固定。标本在5至30牛之间加载200个循环。测量达到5毫米间隙的载荷和极限破坏载荷。在修复后立即进行的生物力学模型中,标准Krakow跟腱修复采用异种移植支架增强后,比标准Krackow修复显著更强且更硬(39.0±8.8对24.4±4.6牛/毫米;P = 0.01)。增强修复组达到极限破坏载荷时的载荷显著高于Krackow组(862.7±174.0对479.5±65.5牛;P < 0.01)。生物学因素仍有待研究,但这种增强方法可为身体状况不佳或有再断裂的患者提供额外的强度。