Division of Internal Medicine, Carmel Medical Center, Haifa, Israel.
Eur J Intern Med. 2012 Apr;23(3):231-5. doi: 10.1016/j.ejim.2011.11.006. Epub 2011 Dec 16.
Venous thromboembolism (VTE) is prevalent and is associated with dire consequences. Many VTE events are related to medical hospitalization, and some of these events are avoidable when appropriate measures are taken. Despite the current knowledge of the prevalence and burden of this disease, many internists are reluctant to prescribe pharmacological prophylaxis to "at-risk" medical inpatients. The purpose of this review is to analyze the reasons for deferring such treatment, in view of the facts as presented in the medical literature. We believe that while the literature supports further emphasis on education and support systems, Internists are deficient of validated tools to decide upon their patient's true risk of clinically overt disease.
静脉血栓栓塞症(VTE)较为常见,并与严重后果相关。许多 VTE 事件与住院治疗相关,且当采取适当措施时,部分事件是可以预防的。尽管目前已经认识到这种疾病的流行程度和负担,但许多内科医生不愿意为“高危”住院患者开具药物预防治疗。鉴于医学文献中的事实,本综述旨在分析推迟此类治疗的原因。我们认为,尽管文献支持进一步强调教育和支持系统,但内科医生缺乏有效的工具来确定其患者发生临床显性疾病的真正风险。