Division of Neurotology and Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery, University of California Irvine, Irvine, CA 92868, USA.
Am J Otolaryngol. 2012 Sep-Oct;33(5):556-61. doi: 10.1016/j.amjoto.2012.01.011. Epub 2012 Mar 3.
The aim of the study was to evaluate various presentations and treatment options for spontaneous cerebrospinal fluid (CSF) leakage originating in the temporal bone.
Clinical data and imaging results for 18 ears (15 patients) presenting with spontaneous CSF leakage originating in the temporal bone were reviewed. Average follow-up period was 13.5 months. The main outcome measure was presence of persistent CSF leak postoperatively. A standard postauricular mastoidectomy was performed.
Fifteen patients diagnosed with spontaneous CSF leakage over an 8-year period including 3 treated for bilateral disease were included in the study. The age ranged between 33 and 83 years. Presenting symptoms included serous otitis media (44%), persistent otorrhea after tympanostomy tube placement (28%), and meningitis (28%). Preoperative diagnosis was made using imaging studies and was substantiated by observation of CSF leakage and dural herniation intraoperatively. Treatment was eustachian tube plugging (5%), mastoidectomy with fat obliteration (61%), middle fossa approach with extradural (17%), intradural repair (5%), or combined middle fossa and transmastoid (TM) approach (11%). Successful treatment was obtained in 17 of the 18 cases. The last 9 patients in the series underwent TM approach alone for repair with no treatment failures.
Repair of defects in tegmen mastoideum and posterior fossa can be successfully achieved on an outpatient basis without regard to size and multitude of defects via TM approach. This approach obviates the need for a craniotomy or lumbar drain.
本研究旨在评估起源于颞骨的自发性脑脊液(CSF)漏的各种表现和治疗选择。
回顾了 18 耳(15 例)起源于颞骨自发性 CSF 漏患者的临床资料和影像学结果。平均随访时间为 13.5 个月。主要观察指标为术后是否存在持续性 CSF 漏。行标准耳后完壁式乳突切除术。
研究纳入了 15 例在 8 年间诊断为自发性 CSF 漏的患者,包括 3 例双侧疾病患者。年龄在 33 岁至 83 岁之间。主要症状包括浆液性中耳炎(44%)、鼓室成形术后持续耳漏(28%)和脑膜炎(28%)。术前诊断通过影像学研究,并通过术中观察 CSF 漏和硬脑膜疝加以证实。治疗方法包括咽鼓管填塞(5%)、乳突切除术伴脂肪填塞(61%)、经颅中窝入路硬膜外修补(17%)、硬膜内修补(5%)或颅中窝和经乳突联合入路(11%)。18 例中有 17 例治疗成功。该系列的最后 9 例患者均采用经乳突单独入路行修补术,无治疗失败。
经乳突单独入路可成功修复鼓室盖和颅后窝的缺损,无需开颅或腰椎引流,且与缺损的大小和数量无关。