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碘海醇(欧乃派克)脊髓造影后癫痫持续状态。

Status epilepticus after myelography with iohexol (Omnipaque).

机构信息

Emergency Medicine Department, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, 1617763141 Tehran, Iran.

出版信息

Am J Emerg Med. 2012 Nov;30(9):2092.e1-3. doi: 10.1016/j.ajem.2011.12.034. Epub 2012 Mar 3.

DOI:10.1016/j.ajem.2011.12.034
PMID:22386347
Abstract

Myelography has been of great use as a diagnostic modality, especially when other modalities were not conclusive.However, considering the invasive nature of myelography, it should receive the attention of medical personnel for them to be aware of its possible complications, especially when newer agents are applied as the contrast media. Myelography could lead to some common adverse effects and complications, but in this case report, we will present one of the most serious and uncommon complications accompanied with myelography using Omnipaque, a nonionic second-generation contrast agent. These complications include lower-extremity myoclonic spasms, tonic seizure leading to status epilepticus, rhabdomyolysis, disseminated intravascular coagulation and anaphylactic shock. Having the knowledge of possible complications and available solutions, particularly fatal ones, could prepare medical staff beforehand for primary and secondary preventions.

摘要

脊髓造影术作为一种诊断方式有很大的用处,特别是当其他方式的结果不确定时。然而,考虑到脊髓造影术的侵袭性,医务人员应该关注它可能带来的并发症,特别是当使用新的造影剂时。脊髓造影术可能会导致一些常见的不良反应和并发症,但在本病例报告中,我们将介绍一种最严重和不常见的并发症,这种并发症伴随着使用非离子型第二代造影剂欧乃派克(Omnipaque)进行脊髓造影术。这些并发症包括下肢肌阵挛性痉挛、强直阵挛导致癫痫持续状态、横纹肌溶解、弥散性血管内凝血和过敏性休克。了解可能出现的并发症及其解决方案,特别是致命的并发症,可以使医务人员提前做好一级和二级预防准备。

相似文献

1
Status epilepticus after myelography with iohexol (Omnipaque).碘海醇(欧乃派克)脊髓造影后癫痫持续状态。
Am J Emerg Med. 2012 Nov;30(9):2092.e1-3. doi: 10.1016/j.ajem.2011.12.034. Epub 2012 Mar 3.
2
Rhabdomyolysis after intraoperative myelography.术中脊髓造影后横纹肌溶解症。
Paediatr Anaesth. 2004 Jun;14(6):509-13. doi: 10.1111/j.1460-9592.2004.01215.x.
3
Myelography with Omnipaque (Iohexol) using basic radiographic facilities: the main adverse effects.
Cent Afr J Med. 1996 Jul;42(7):192-5.
4
Absence status epilepticus resulting from metrizamide and omnipaque myelography.由甲泛葡胺和碘海醇脊髓造影引起的失神癫痫持续状态。
Clin Electroencephalogr. 1988 Jan;19(1):37-42. doi: 10.1177/155005948801900110.
5
A rare case of disseminated intravascular coagulation caused by the nonionic contrast medium iohexol.一例由非离子型造影剂碘海醇引起的弥散性血管内凝血罕见病例。
J Urol. 1995 Jun;153(6):1901-3.
6
[Speech disturbance following myelography with iohexol: a case report].
No To Shinkei. 2005 Sep;57(9):796-9.
7
Lumbar myelography with iohexol. Adverse effects compared with spinal puncture.碘海醇腰椎脊髓造影。与腰椎穿刺相比的不良反应。
Acta Radiol. 1988 Nov-Dec;29(6):637-40.
8
Generalized seizures following myelography with iohexol (Omnipaque).使用碘海醇(欧乃派克)进行脊髓造影后出现全身性癫痫发作。
J Spinal Disord. 1990 Mar;3(1):59-61.
9
[Disseminated intravascular coagulation secondary to the intravenous administration of iodinated contrast media].
Rev Esp Anestesiol Reanim. 1996 Jan;43(1):43-4.
10
Status epilepticus following iohexol myelography.
Neuroradiology. 1993;35(4):322-3. doi: 10.1007/BF00602626.

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2
It Is Not Necessary to Discontinue Seizure Threshold-Lowering Medications Prior to Myelography.没必要在脊髓造影前停止降低癫痫发作阈值的药物。
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Lumbar puncture under fluoroscopy guidance: a technical review for radiologists.
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Critical Assessment of Myelography Practices: A Call for Rational Guideline Revision.脊髓造影术实践的批判性评估:呼吁修订合理的指南。
AJNR Am J Neuroradiol. 2018 Dec;39(12):2378-2384. doi: 10.3174/ajnr.A5867. Epub 2018 Nov 1.
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Vasogenic Cerebral Edema following CT Myelogram with Nonionic Omnipaque 300.CT脊髓造影使用非离子型碘海醇300后发生的血管源性脑水肿
Case Rep Neurol Med. 2018 May 22;2018:2761872. doi: 10.1155/2018/2761872. eCollection 2018.
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The Use of Contrast in Caudal Epidural Injections under Image Intensifier Guidance: Is It Necessary?影像增强器引导下骶管硬膜外注射中造影剂的使用:有必要吗?
Clin Orthop Surg. 2017 Jun;9(2):190-192. doi: 10.4055/cios.2017.9.2.190. Epub 2017 May 8.