Quies W, Ledderhos C
Institut für Physiologie des Bereiches Medizin Ernst-Moritz-Arndt-Universität, Greifswald.
Z Gesamte Hyg. 1990 Sep;36(9):513-6.
In acute hypoxia or at pharmacological stimulation of the peripheral arterial chemoreceptors by almitrine, a transient natriuresis and diuresis occurs. Depending on the starting level, e.g. on the state of water diuresis or the osmotic diuresis, the renal excretion responded differently in our examinations. In water diuresis the water excretion increased isolatedly. In the opposite to the osmotic diuresis, the natriuresis did not increase. This response might be based on the proximal inhibition of the sodium and water reabsorption at following augmented distal sodium reabsorption and suppressed distal water reabsorption. In this way the organism is able to respond with increased water excretion at sodium excretion kept constant or with diuresis and natriuresis when arterial chemoreceptors are stimulated.
在急性缺氧或使用氨苯碱对外周动脉化学感受器进行药理刺激时，会出现短暂的利钠和利尿现象。根据起始水平，例如水利尿或渗透性利尿的状态，在我们的检查中肾脏排泄的反应有所不同。在水利尿时，水排泄单独增加。与渗透性利尿相反，利钠作用并未增加。这种反应可能是基于近端对钠和水重吸收的抑制，随后远端钠重吸收增加而远端水重吸收受到抑制。通过这种方式，当动脉化学感受器受到刺激时，机体能够在钠排泄保持恒定的情况下增加水排泄，或者出现利尿和利钠现象。
