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无症状性心肌缺血

[Asymptomatic myocardial ischemia].

作者信息

Loskot F, Novotny P

机构信息

Herz- und Kreislaufzentrum, Rotenburg.

出版信息

Z Gesamte Inn Med. 1990 Jul 1;45(13):370-3.

PMID:2238747
Abstract

Silent (asymptomatic) myocardial ischemia (SMI) is defined as a transient alteration in myocardial perfusion in the absence of chest pain or the usual anginal equivalents. Patients may be classified as having one of the three types of SMI: type A--totally asymptomatic patients with no history of angina or myocardial infarction; type B--asymptomatic patients with previous myocardial infarction; type C--patients with angina and asymptomatic ischemic episodes. SMI has been found in 2.5% of all healthy males aged 40-59 and in 20% of all postinfarction patients. In type C-patients, 80% has been found to have asymptomatic ischemic episodes in addition to typical angina pectoris. The frequency of SMI may be up to three or four times that of anginal attacks. SMI patients have generally reduced sensitivity to pain an differences in severity an duration of ischemic episodes. Diagnosis is based on screening by means of exercise testing in patients working in specific professions (like pilots, busdrivers etc.), in postinfarction patients and in patients after unstable angina pectoris and after coronary bypass surgery or coronary angioplasty. Prognosis is the same as in asymptomatic ischemia. SMI is an indicator of instability in certain groups of patients (post infarction, after unstable angina pectoris). SMI persisting after medical therapy of unstable angina is associated with adverse short-term-prognosis, therefore coronary surgery or angioplasty is indicated.

摘要

无症状性心肌缺血(SMI)被定义为在无胸痛或通常的心绞痛等效症状情况下心肌灌注的短暂改变。患者可被归类为患有以下三种类型的SMI之一:A型——完全无症状且无心绞痛或心肌梗死病史的患者;B型——有既往心肌梗死病史的无症状患者;C型——有心绞痛且有无症状性缺血发作的患者。在所有40 - 59岁的健康男性中,2.5%被发现患有SMI,在所有心肌梗死后患者中这一比例为20%。在C型患者中,80%被发现除典型心绞痛外还有无症状性缺血发作。SMI的发作频率可能是心绞痛发作频率的三到四倍。SMI患者通常对疼痛的敏感性降低,缺血发作的严重程度和持续时间也存在差异。诊断基于对从事特定职业的患者(如飞行员、公交车司机等)、心肌梗死后患者、不稳定型心绞痛后患者以及冠状动脉搭桥手术或冠状动脉成形术后患者进行运动试验筛查。预后与无症状性缺血相同。SMI是某些患者群体(心肌梗死后、不稳定型心绞痛后)病情不稳定的一个指标。不稳定型心绞痛药物治疗后仍持续存在的SMI与不良短期预后相关,因此建议进行冠状动脉手术或血管成形术。

相似文献

1
[Asymptomatic myocardial ischemia].无症状性心肌缺血
Z Gesamte Inn Med. 1990 Jul 1;45(13):370-3.
2
[Silent myocardial ischemia].
Z Kardiol. 1989;78 Suppl 2:145-9; discussion 159.
3
Silent ischemia: a timely aspect in coronary artery disease.无症状性缺血:冠状动脉疾病中的一个重要方面。
Herz. 1987 Oct;12(5):314-7.
4
[Characteristics and clinical significance of silent myocardial ischemia during ambulatory electrocardiographic monitoring in patients with ischemic heart disease].[缺血性心脏病患者动态心电图监测中无症状性心肌缺血的特征及临床意义]
Hokkaido Igaku Zasshi. 1990 Nov;65(6):583-94.
5
[Long-term prognosis in unstable angina].[不稳定型心绞痛的长期预后]
Praxis (Bern 1994). 1995 Feb 21;84(8):220-4.
6
[Detection and prognostic value of silent myocardial ischemia].[无症状性心肌缺血的检测及预后价值]
Arch Mal Coeur Vaiss. 1993 Jun;86 Spec No 3:19-23.
7
[Prognostic implications of exercise induced silent myocardial ischemia in patients with angina pectoris].[运动诱发无症状心肌缺血在心绞痛患者中的预后意义]
Kokyu To Junkan. 1991 Aug;39(8):825-30.
8
Percutaneous transluminal coronary angioplasty in patients with silent myocardial ischemia during exercise testing.
Herz. 1987 Dec;12(6):392-7.
9
[Silent myocardial ischemia].
Pol Merkur Lekarski. 1999 Oct;7(40):153-8.
10
The prognostic importance of asymptomatic ischemic episodes in patients with unstable angina pectoris.不稳定型心绞痛患者无症状缺血发作的预后重要性。
Herz. 1987 Oct;12(5):336-40.

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