Kath R, Schmidt C G
Innere Klinik und Poliklinik (Tumorforschung), Westdeutsches Tumorzentrum, Universitätsklinikum Essen.
Zentralbl Chir. 1990;115(13):785-92.
The heterogeneity of cells capable of metastasation has proved to be the greatest obstacle to successful treatment or to prevention of metastatic diseases. This variety appears to be attributable to processes of selection. Cytobiological investigations which are helpful in casting some light at selective mechanisms of metastasation may, perhaps, make substantive contributions to cancer therapy.
能够发生转移的细胞的异质性已被证明是成功治疗或预防转移性疾病的最大障碍。这种多样性似乎归因于选择过程。有助于阐明转移选择性机制的细胞生物学研究可能会对癌症治疗做出重大贡献。
