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超微孔β-磷酸三钙(Vitoss)作为骨移植替代物用于良性和低级别恶性骨肿瘤空洞性缺损的有效性。

Effectiveness of ultraporous β-tricalcium phosphate (vitoss) as bone graft substitute for cavitary defects in benign and low-grade malignant bone tumors.

作者信息

Van Hoff Corey, Samora Julie Balch, Griesser Michael J, Crist Martha K, Scharschmidt Thomas J, Mayerson Joel L

机构信息

Department of Orthopaedics, Ohio State University Medical Center, Columbus, Ohio 43210-1280, USA.

出版信息

Am J Orthop (Belle Mead NJ). 2012 Jan;41(1):20-3.

Abstract

We retrospectively evaluated healing with ultraporous β-tricalcium phosphate (β-TCP [Vitoss; Orthovida, Malvern, Pennsylvania]) bone graft in patients who underwent surgical excision or curettage of benign bone lesions subsequently filled with bone void filler. Twentynine patients were treated with curettage and ultraporous β-TCP morsels. Radiologic defect size at initial postoperative presentation and subsequent visits (minimum follow-up, 6 months) was evaluated. Results suggested that an ultraporous β-TCP synthetic bone graft is effective in managing bone voids. The vast majority of patients who undergo curettage for benign bone lesions can expect to have complete or near complete healing of these defects within 6 months of their surgical procedure with use of ultraporous β-TCP morsels.

摘要

我们回顾性评估了接受手术切除或刮除良性骨病变后用骨空隙填充剂填充的患者使用超微孔β-磷酸三钙(β-TCP[Vitoss;Orthovida,宾夕法尼亚州马尔文])骨移植的愈合情况。29例患者接受了刮除术并使用超微孔β-TCP碎粒治疗。评估了术后初始表现及随后随访(最短随访6个月)时的放射学缺损大小。结果表明,超微孔β-TCP人工骨移植在处理骨空隙方面是有效的。绝大多数因良性骨病变接受刮除术的患者,在手术6个月内使用超微孔β-TCP碎粒有望实现这些缺损的完全或接近完全愈合。

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