Incecik Faruk, Hergüner Mihriban Ozlem, Ozcan Kenan, Altunbaşak Sakir
Division of Pediatric Neurology, Department of Pediatrics, Cukurova University Faculty of Medicine, Adana, Turkey.
Turk J Pediatr. 2011 Nov-Dec;53(6):709-10.
Drug-induced dystonic reactions are a common presentation to the emergency department and typically occur with drugs like chlorpromazine, haloperidol and metoclopramide. There are no reports in the literature of dystonic reaction caused by albendazole. We report a case of albendazole-induced acute dystonic reaction whose symptoms completely resolved after the discontinuation of the drug. Even though dystonia side effects of albendazole are rare, it can induce an alarming dystonia in some sensitive children. The mechanism of dystonia is unclear.
药物性肌张力障碍反应是急诊科常见的病症,通常由氯丙嗪、氟哌啶醇和甲氧氯普胺等药物引起。文献中尚无阿苯达唑引起肌张力障碍反应的报道。我们报告一例阿苯达唑诱发的急性肌张力障碍反应病例,停药后症状完全缓解。尽管阿苯达唑的肌张力障碍副作用罕见,但在一些敏感儿童中可诱发严重的肌张力障碍。肌张力障碍的机制尚不清楚。