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[罗兹市两波疫情中2009年甲型H1N1流感儿童病例]

[Cases of children with influenza AH1N1/2009 in the district of Lodz in two epidemic waves].

作者信息

Majda-Stanisławska Ewa, Sobieraj Iwona

机构信息

Klinika Chorób Zakaźnych i Hepatologii Uniwersytetu Medycznego w Łodzi.

出版信息

Przegl Epidemiol. 2011;65(4):609-14.

PMID:22390048
Abstract

High influenza morbidity due to new antigenic strain AH1N1 was announced in Mexico in spring 2009. Influenza pandemic caused by the virus AH1N1/2009 spread around the world. Two pandemic waves were noted in most European countries: the first one was due to summer months migration, the second wave started in the beginning of common influenza season. We present features of both waves in children from the district of Lodz. We describe mild clinical course in 14 children who came from holiday in Spain with influenza and who were hospitalized and treated with osltamimivir due to unpredictable course of new influenza. We also present 22 influenza cases of the autumn pandemic wave, when children with severe complications of influenza and children from high risk groups were hospitalized and treated with antivirals. Experience that we have gained during 2009 influenza pandemic indicates that International Influenza Control System is very efficient, however more flexibility is required in application of treatment and prophylaxis procedures with new influenza strains. Applied methods of control should mostly depend on the virulence of pandemic strain.

摘要

2009年春季,墨西哥宣布因新型抗原性毒株AH1N1导致流感发病率居高不下。由AH1N1/2009病毒引发的流感大流行蔓延至全球。大多数欧洲国家出现了两波大流行:第一波是由于夏季的人员流动,第二波始于普通流感季节开始之时。我们呈现了罗兹地区儿童这两波流感的特征。我们描述了14名来自西班牙度假地、患流感且因新型流感不可预测的病程而住院并接受奥司他韦治疗的儿童的轻症临床过程。我们还介绍了秋季大流行波中的22例流感病例,当时患有严重流感并发症的儿童以及高危群体的儿童住院并接受了抗病毒治疗。我们在2009年流感大流行期间获得的经验表明,国际流感防控体系非常有效,然而在应用针对新型流感毒株的治疗和预防程序时需要更大的灵活性。所采用的防控方法应主要取决于大流行毒株的毒力。

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