Valeeva G R, Khazipov R N, Nikol'skiĭ E E
Ross Fiziol Zh Im I M Sechenova. 2011 Nov;97(11):1179-86.
GABA (gamma-aminobutyric acid) is the main inhibitory mediator in central nervous system. However, at early stages of ontogenesis, GABA has an excitatory effect on immature neurons. This review surveys modern concepts of the mechanisms of GABAergic excitation and physiological role of excitatory GABA in generation of patterns of network activity in developing brain.
γ-氨基丁酸（GABA）是中枢神经系统中的主要抑制性介质。然而，在个体发育的早期阶段，GABA对未成熟神经元具有兴奋作用。本文综述了关于GABA能兴奋机制的现代概念以及兴奋性GABA在发育中大脑网络活动模式产生中的生理作用。
