Bouharras M, Deldime P, Storck M
Service de chirurgie, Clinique et Maternité St-Joseph, Arlon.
Acta Chir Belg. 1990 Jul-Aug;90(4):172-6.
Chondrosarcoma is a slow-growing malignant tumor, with a mainly local infiltration, usually arising from skeletal cartilaginous cells. However, a few such neoplasms also arise from extraskeletal mesenchymal cells. Metastasis are usually seen with undifferentiated tumors (grade III), mainly within the lungs. The best treatment associates total surgical resection with chemotherapy. Radiotherapy is of poor use. Isolated pulmonary metastasis can be profitably withdrawn. Prognosis is about of 75% of survival after 10 years, in case of well-differentiated tumors (grade I). The prognosis is far worse for undifferentiated tumors (grade III), turning around 10% of survival after 10 years.
软骨肉瘤是一种生长缓慢的恶性肿瘤,主要呈局部浸润性生长,通常起源于骨骼软骨细胞。然而,也有少数此类肿瘤起源于骨骼外间充质细胞。转移通常见于未分化肿瘤(III级),主要发生在肺部。最佳治疗方法是手术完全切除联合化疗。放疗效果不佳。孤立性肺转移灶可通过手术切除获益。对于高分化肿瘤(I级),10年后的预后生存率约为75%。未分化肿瘤(III级)的预后则差得多,10年后的生存率约为10%。