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[冠状动脉血栓形成所致猝死的病理特征]

[Pathological characteristics of sudden death caused by coronary thrombosis].

作者信息

Zhao Xiao-Jie, Yang Ling-Yun, Yang Yu-Jie, Bai Jie, Fan Shuan-Liang, Wang Zhen-Yuan

机构信息

Department of Forensic Science, Medical College, Xi'an Jiaotong University, Xi'an 710061, China.

出版信息

Fa Yi Xue Za Zhi. 2011 Dec;27(6):434-7.

PMID:22393593
Abstract

OBJECTIVE

To explore medico-legal characteristics of sudden death caused by coronary heart disease combined with coronary thrombosis.

METHODS

Ninety-six cases of sudden death caused by coronary heart disease were collected and divided into two groups: thrombus positive and thrombus negative groups. The time onset, induction and pathological features of coronary artery disease were analyzed.

RESULTS

Two groups showed man-dominant population. There were no statistical significant differences in season, circadian rhythm and induction factor. The thrombus positive group (age < 40) showed a higher disease incidence. Heart weight and degree of coronary stenosis were lower in thrombus positive group. However, there was no statistical difference in the number of atherosclerotic coronary arteries (> or = 2), the length of coronary lesions and myocardial infarct. But thrombosis positive group showed lower tendency.

CONCLUSION

Two groups are man-dominant population and similar induction factor, lesion position, mechanism of death. But thrombus positive group appeared more in a younger population and the degree of coronary stenosis is milder than thrombus negative group. Forensic pathologists should pay more attention to these characteristics in death investigation.

摘要

目的

探讨冠心病合并冠状动脉血栓形成所致猝死的法医学特征。

方法

收集96例冠心病猝死病例,分为血栓阳性组和血栓阴性组。分析冠心病的发病时间、诱发因素及病理特征。

结果

两组均以男性为主。在季节、昼夜节律和诱发因素方面无统计学显著差异。血栓阳性组(年龄<40岁)发病率较高。血栓阳性组心脏重量和冠状动脉狭窄程度较低。然而,在粥样硬化冠状动脉数量(≥2支)、冠状动脉病变长度和心肌梗死方面无统计学差异。但血栓阳性组呈较低趋势。

结论

两组均以男性为主,诱发因素、病变部位、死亡机制相似。但血栓阳性组在较年轻人群中出现较多,冠状动脉狭窄程度比血栓阴性组轻。法医病理学家在死亡调查中应更多关注这些特征。

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